IBB provides shared research facilities that support life sciences, biomedical engineering, and biotechnology innovation across Georgia Tech. IBB’s core labs offer advanced capabilities in imaging, sequencing, proteomics, metabolomics, histology, biomechanics, and biopolymer analysis.

Petit Institute for Bioengineering and Bioscience (IBB) | Research

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3D Printing and Medical Device Fabrication

  • 3D printing
  • Fabrication of medical grade parts
  • Fabrication of biocompatible parts

Applied Bioinformatics

  • Bioinformatics
  • Computational genomics
  • Transcriptomics analysis
  • Molecular typing
  • Machine learning and biostatistical analysis

Biomechanics

  • Compression testing
  • Uniaxial tensile testing
  • Uniaxial torsion testing
  • Cyclic fatigue testing
  • fFexural testing

Biomolecular Analysis

  • Laser capture microdissection
  • Gel, blot and tissue Imaging
  • PCR Analysis
  • Freeze drying
  • Fluorescence absorbance and luminescence analysis
  • Scintillation counting
  • High-performance and ultracentrifugation
  • Nucleofection
  • Sample homogenization
  • In vivo imaging (fluorescence and bioluminescence)

Biopolymer Characterization

  • HPLC
  • FPLC
  • Circular dichroism/fluorescence
  • Size exclusion chromatography
  • Multimode DLS
  • Ultracentrifugation
  • Multimode DSF
  • Stopped flow
  • High-throughput absorbance/ fluorescence/chemiluminescence
  • ITC
  • Stop flow kinetics analysis
  • Analytical ultracentrifugation
  • Protein stability analysis
  • High-performance and ultracentrifugation

Cellular Analysis and Cytometry

  • Flow Cytometry Analysis (Up to 18 color conventional, Up to 40 color spectral)
  • Fluorescence Activated Cell Sorting (2-way, 4-way, 6-way, and plates with index sorting)
  • Imaging cytometry
  • Mass Cytometry (Helios)
  • Tissue Imaging Mass Cytometry (Hyperion)
  • Cell and particle enumeration and characterization

Genome Analysis

  • qRT-PCR & RT-PCR
  • Nucleofection
  • Single cell isolation (large sample number)
  • Single cell isolation (small sample number)
  • Digital drop PCR

Histology

  • Automated sample handling
  • Automated Colony picking
  • Library screening
  • Nucleofection Project Customization & Optimization
  • Esoteric and Non-routine Histology
  • Cryopreservation & Embedding
  • Paraffin Processing & Embedding
  • Resin & Paraffin Microtomy
  • Basic & Intricate Cryotomy
  • Hematoxylin & Eosin and Specialized Staining
  • Consulting and Training
  • Sample Decalcification
  • Resin Embedding (GMA, MMA & Epoxy)
  • Immunohistochemistry & Immunofluorescence
  • Plant Physiology
  • Exakt Grinding System
  • Precision Sectioning w/ Diamond Saw
  • Routine Histological Analysis

Image Data Analysis

  • 3d Image Analysis
  • Microscopy, CT, MRI Image Stack Reconstruction
  • 3d Quantitative Analysis, 3d-Printables STL File Outputs
  • High content 2d Image Analysis for Biomarkers

Magnetic Resonance Imaging

  • Small Animal MRI
  • Engineering Applications of MRI
  • Magnetic Resonance Spectroscopy
  • Flow-MRI
  • MRI technology

Microcomputed Tomography (Micro cT)

  • Sample cT
  • in vivo cT
  • 3D reconstruction of cT slices
  • cT image analysis

Molecular Evolution

  • Next Generation Sequencing
  • Sanger Sequencing
  • Whole Plasmid Sequencing
  • Automated Gel Extraction Using the Blue Pippin
  • DNA Fragment Size Selection
  • Phage Display
  • Surface Display
  • Oligonucleotide Synthesis
  • Automated Colony Picking
  • Fragment Analysis
  • Automated DNA and RNA Extraction
  • Cloning
  • Error-prone PCR

Molecular Evolution and HT DNA Sequencing

Optical Microscopy

  • Laser scanning confocal
  • Spinning disk confocal
  • Multi-photon excitation- inverted and upright
  • Lightsheet
  • Widefield
  • TIRF microscopy
  • Super resolution SIM
  • Super resolution-dSTORM and PALM
  • Swept field Confocal

Systems Mass Spectrometry (Metabolomics)

  • Non-targeted polar and/or non-polar metabolomic assays
  • Targeted assays
  • Exact mass measurement
  • Mass Spectrometry Imaging
  • Sample preparation, data collection, data processing, data analysis, annotation, and interpretation

Systems Mass Spectrometry (Proteomics)

  • Discovery and targeted proteomics
  • Protein identification and quantification
  • Protein-protein interaction studies
  • Posttranslational modification analysis
  • Intact protein analysis, protein complex characterization